FDA approval of the B-cell depleting monoclonal antibody inebilizumab-cdon (Uplizna) a year ago for immunoglobulin (Ig)G4-related disease (RD) has cemented B-cell depletion as current first-line ...

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A team led by Mass General Brigham researchers demonstrated that inebilizumab reduced the risk of symptoms by 87% in patients with the rare affliction known as immunoglobulin G4–related disease ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Uplizna met all primary and secondary endpoints for ...

The patient in the current case report showed manifestations of both AAV and IgG4-RD; his improvement linked to steroid/cyclophosphamide treatment underscores the need for integrated diagnosis and ...

Arezou Khosroshahi, MD, professor of medicine at Emory University, discusses the importance of imaging to understand organ involvement and track changes over time. (2:32) Using univariate and ...

Thalidomide demonstrated superior efficacy in preventing the relapse of immunoglobulin G4–related disease (IgG4-RD) during a 12-month follow-up period in a placebo-controlled trial. The treatment ...

The study, titled “Association of IgG4-Related Disease with Human Inborn Errors of Immunity,” involved 18 patients diagnosed with IgG4-RD, all of whom underwent Whole Exome Sequencing (WES) to examine ...

Nika Beamon thought she was going to die. The former college athlete always played high-impact sports. Rugby, ice hockey, you name it. Always knocked down but toughing it out. By the time she was a ...

Advances Amgen (AMGN)'s Leadership in CD19 Directed, B-Cell Depletion Therapies for Serious Autoimmune Diseases Including NMOSD, IgG4-RD and gMG THOUSAND OAKS, Calif., April 3, 2025 /PRNewswire/ -- ...

Renal disease is a rare but potentially severe manifestation of IgG4-RD. An elderly man with immunoglobulin G4-related disease (IgG4-RD) with kidney involvement and monoclonal gammopathy was ...

IgG4-related disease is a multifaceted, systemic fibroinflammatory condition that can affect virtually any organ, with autoimmune pancreatitis representing one of its most well‐characterised ...