RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior—capturing not just genetic ...

The answer depends on the questions you’re trying to answer, as well as the origin, quantity, and quality of your samples. In this article, we’ll briefly discuss several RNA-seq workflows, how they ...

A new single‑cell method, CIPHER‑seq, measures RNA and proteins together to reveal real‑time cytokine signaling.

Genes are expressed when messenger RNA is made from DNA, which is then translated into proteins. Researchers use single-cell and bulk RNA-seq analysis to study gene expression, creating vast amounts ...

Monitoring PD-L1 Expression on Circulating Tumor–Associated Cells in Recurrent Metastatic Non–Small-Cell Lung Carcinoma Predicts Response to Immunotherapy With Radiation Therapy Gene fusions play a ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...