AI algorithm identifies cells across diverse biological images, cutting hours of manual labeling

Imaging is a critical technique in biology—from identifying cancerous cells in biopsies to observing how immune cells like ...
eLife

Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state

The dorsal raphe nucleus (DRN) serotonergic (5-HT) system has been implicated in regulating sleep and motor control; however, its specific role remains controversial. In this study, we found that ...
eLife

Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization

HIV-1 envelope glycoprotein (Env), a gp120–gp41 trimer, undergoes coordinated conformational changes that drive membrane fusion and allow immune evasion by transiently concealing ...
Nature

Deep learning for image analysis

This Collection calls for submissions of original research into techniques that facilitate the advancement of deep learning for image analysis and object detection, driving computer vision forward and ...